Crossover Kava and Kratom Study

A Randomized, Double-Blind, 3-Period Crossover, Pharmacokinetic Study in Healthy Adults to Compare Combined Kava and Kratom Supplementation with Kava or Kratom Alone Under Fasted Conditions

The study will consist of a total of 16 visits to our clinic (located in Guelph, Ontario) and 4 remote phone calls over a 22-week period. If you complete the study in its entirety, compensation will be up to $3,550 for your time and travel to the clinic.

The purpose of this study is to assess the pharmacokinetic (PK) properties of combined Kava and Kratom compared to Kava and Kratom individually in healthy adults.

Only a limited amount of spots available.

You may be eligible if you:

Are between 21 to 55 years old

Have a BMI between 18.5 to 29.9 kg/m²

Are in good general health

Do not regularly use tobacco, nicotine, or cannabis

Are not taking any prescription medications (including hormonal birth control)

Crossover Kava and Kratom Study

Participation will include:

16 visits to our clinic (located in Guelph, ON) and 4 remote phone calls over a 22-week period
6 in-clinic visits lasting up to 16 hours each
Consuming a liquid herbal supplement containing Kava root extract and/or Kratom leaf powder once daily with food during the treatment periods
Multiple blood draws and urine sample collections

Compensating up to $3,550

SEE IF YOU QUALIFY

How It Works:

Facility Features

We take pride in our bright, modern clinic that we continue to upgrade to ensure a comfortable clinical trial experience for you. Click here to take a virtual tour of our space.