A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of an Investigational Herbal Supplement Containing Kava Extract and Kratom Leaf Powder on Self-Reported Stress and Pharmacokinetic Profile in Healthy Adults
There are 2 portions to this study, the Main Group and Sub Group. You can not participate in both groups. The Main Group will consist of a total of 8 visits to our clinic (located in Guelph, ON) and 1 remote phone call over a 13-week period. The Sub Group will consist of a total of 15 visits to our clinic (located in Guelph, ON) and 1 remote phone call over a 13-week period. If you complete the study in its entirety, compensation will be $2,000 (Main Group) and $5,600 (Sub Group) for your time and travel to the clinic.
The purpose of this study is to assess the effect of the test product on self-reported stress compared to the placebo.
Only a limited amount of spots available.
You may be eligible if you:
Are between 21 to 55 years old
Have a BMI between 18.5 to 29.9 kg/m²
Are in good general health
Have self-reported stress
Are not taking any prescription medications (excluding hormonal birth control)
Kava and Kratom Study
Participation will include:- 8 visits to our clinic (located in Guelph, ON) and 1 remote phone call over a 13-week period (Main Group)
- 15 visits to our clinic (located in Guelph, ON) and 1 remote phone call over a 13-week period (Sub Group)
- Oral consumption of study product (liquid formulation)
- Multiple blood draws, urine sample collections, and saliva sample collections
How It Works:

Facility Features
We take pride in our bright, modern clinic that we continue to upgrade to ensure a comfortable clinical trial experience for you. Click here to take a virtual tour of our space.

Free wifi available throughout facility

Accessible facility

Private rooms available for calls

Certified, experienced and friendly staff

Comfortable seating options

24/7 access to staff
The Team Behind The Scenes
At Apex Trials, your safety is our top priority. Our team of qualified staff are here to ensure everything runs smoothly.

Dr. Anthony Bier
Medical Director

Supreet Gill
Clinical Research Coordinator II

Neuza Pereira
Clinical Research Coordinator I

Taylor Manning
Clinical Research Coordinator I
